E-Newsletter
An Electronic Publication of the North Central Massachusetts Chamber of Commerce
Inside this edition, you’ll discover the latest Chamber initiatives and success stories from across our region. From economic development projects and upcoming networking events to policy updates and workforce training opportunities, we’re keeping you connected to what matters most for your business and North Central Massachusetts.
The North Central Massachusetts Chamber of Commerce is here to help – with trusted resources, a strong business network, and a support system to keep your business and the region moving forward
The last few months have easily been the most disruptive anyone has experienced since the Second World War. Not only has the nation been forced to contend with a public health crisis, but the ensuing orders to shutter and shelter in place have wreaked havoc on our economy. Both Beacon Hill and Capitol Hill have taken drastic action to face this duel challenge, and the Chamber has actively worked to ensure that the needs of North Central Massachusetts and our employers are addressed by these efforts.

Governor Baker addresses the business community at a Good Morning North Central event last winter.
When Governor Baker announced the establishment of a reopening taskforce in May, we were quick to submit recommendations encouraging them to ensure clarity in their guidance and prioritize the needs of small businesses. We have continued this advocacy since then, with Chamber staff serving on local reopening committees and participating in weekly calls with the Secretary of Housing and Economic Development- who cochairs the state’s taskforce. This approach has proven effective, allowing us to ensure businesses remain abreast of the latest developments while helping to improve communications between state and municipal officials as they navigate the reopening process.
As with many things, this crisis has also disrupted the state’s legislative calendar. A number of major bills – including transportation reform, climate change and health care – have been overtaken by COVID-19’s immediate urgency. Lawmakers anticipate the state will absorb billions of dollars in lost revenues and increased costs as it works to simultaneously contain the virus and address the ensuing economic fallout. This has been compounded by uncertainty regarding federal aid, creating a significant challenge for the Legislature as they work to develop a balanced budget for the fiscal year that began July 1, 2020.
Given this lack of clarity, the State House is expected to pass a series of one twelfth budgets for now, funding state operations from month to month. Unfortunately, though this allows lawmakers to adjust spending as revenue figures come into focus, it creates uncertainty for municipalities, which rely on state aid for their own budgets. In turn, this impacts school funding decisions and the availability of other services. It could also affect non-profits and state contractors were the Commonwealth to eliminate certain local programs or infrastructure projects. Of further concern are calls to increase taxes in an effort to bridge revenue shortfalls. This would exacerbate the current crisis, slowing investment, hiring, and – ultimately – recovery.
On the federal level, Congress recently passed an extension of the PPP stimulus program through August 8. There are also reports that Congress is planning to pass another stimulus package, which may also include a consensus on state financial aid. The Chamber staff has remained in close contact with national partners and the region’s Congressional Delegation on these issues.
The Chamber will continue to monitor issues important to our members and region at the local, state and federal levels. If you have any questions or concerns, please reach out to the Chamber’s public affairs manager- Christopher McDermott- at (978) 353-7600 ext. 224 or . We want your voice to be heard.
This article is from the latest Chamber Report
How a Leominster, MA company is providing resources and expertise to support national and worldwide vaccine production

Nelson Landrau, CEO/Founder of Landrau Scientific Innovations
Massachusetts has encouraged and supported Biopharmaceutical R&D and large-scale Biologics manufacturing throughout the last 30+ years and has become one of the world leaders in development of new technology platforms. Influenza, SARS, and the recent COVID-19 pandemic, have increased the demand for novel vaccine production technologies to bring these vaccines to market quickly and in large quantities.
This demand has stimulated development of new mRNA-based vaccines by local companies in the Boston area. These new oligonucleotide-based vaccines offer great flexibility with respect to production and applications. This scientific approach will enable any protein to be encoded and expressed by an in vitro transcribed mRNA. In principle enabling the development of wide range of prophylactic and therapeutic vaccines to fight a broad range of diseases. To illustrate this diversity, this technology platform is being applied to fight diseases such as viral infections, cancer, and protein replacement therapy. During the production of this novel therapy only the mRNA sequence of the therapeutic target molecule is optimized. This enables diverse products to be manufactured using the same established production process, saving time and reducing cost as compared with other vaccine platforms.
Although mRNA therapy is diverse and can create new vaccines in relatively short time period (as compared to other vaccine technology approaches) new manufacturing challenges have arisen to produce the large quantities of these novel vaccines to fight outbreaks such as COVID-19. As we react to this pandemic with this new class of vaccines based on mRNA and large molecule biologics, such as monoclonal antibodies future large-scale purification workflows will be challenged to meet production goals, regulatory requirements, and cost. Large scale production, packaging and formulation to facilitate long term storage and deployment of these new vaccines will be key to their success. For example, mRNA-based vaccines are being formulated in charged liposomes to enhance their intra-muscular uptake and delivery to the body’s immune system leading to in vivo production of therapeutic and viral neutralizing autoantibodies.
To meet some of these vaccine production demands several new purification technologies are under development in Leominster MA, to accelerate bringing these COVID-19 vaccines to market; 1) Immunoaffinity resins for harvesting recombinant vaccine candidates from cell culture. This approach, taken by the University of Queensland for their “clamp” viral antigen was first evaluated on a new orientated immobilization affinity bioprocess optimized resin developed in by LANSI. This new resin offers high antibody binding capacity while preserving full antibody-antigen binding efficiency. 2) mRNA vaccine candidates generated by in vitro transcription are being purified on oligo dT affinity resins targeting Poly A+ sequences on the 3’ end of the mRNA molecule. Existing first generation R&D oligo-dT affinity resins were based on cellulose beads not fully optimized for large-scale bioprocess applications. A new cellulose-based Oligo dT resin is under development at LANSI in collaboration with the Oligo Factory (Holliston, MA) based on resin beads that have been optimized for large scale bioprocess applications. Formulation of these novel vaccine candidates to confer stability and enhanced immunogenicity and delivery are in development at LANSI to support bringing these new vaccine molecules to market.
If your company has an mRNA or expressed protein viral antigen that you are looking for assistance in scale-up, purification, or formulation, please feel free to reach out to us for a complimentary confidential consultation at 978-537-2890 or write to us at info@lansi.tech. We have many years of experience in these fields and we are available to help you with your technical and product development needs.
Being a member of the North Central Massachusetts Chamber provides members with many opportunities to gain valuable information and connections. We are always on the lookout for valuable content that would be on interest to our members and communities. In an effort to provide an avenue to more easily access the vast array of the knowledge and expertise that our members possess, we are now offering exclusive Guest Columnist articles for the benefit of our members. As a membership based organization, submissions will only be considered from members at the Business Choice level and above.
This is a great opportunity to position your business as a thought leader and expert. Columns should not be self-promotional or sales oriented ,and should consist of content that would be useful to businesses, including tips, answers to important questions and any insights that would be helpful to fellow members. By participating, members have the chance to better inform, educate and aid in the development of other members and the North Central Massachusetts region.
Please contact David Ginisi, Marketing and Communications Manager, if you are interested in participating: | 978.353.7600 x240

Once the major financial hurdles have been addressed, handing a family business over to the next generation can be handled in a variety of ways to suit your personal needs and goals. Obtaining professional help for determining any tax or legal issues should be placed at the top of the agenda. We value our local businesses, and their commitment to our community. Our guidelines can help you identify what items need to be addressed to ensure a seamless transition when handing off the keys to the store to the next generation.
Many local businesses have been in the same family for years. Your children may well have worked in the store growing up, and as they have gotten older, attended business meetings and begun to learn the ropes. The ability to help them get started while you are still able to advise and help them as problems arise is a wonderful opportunity for everyone.
Tips for Successfully Handing off the Family Business Keys to the to the Next Generation
As the current owner, and possibly the person who started the store, you will need to determine how much, if any, monetary compensation is required. The business can be transferred in various ways, gifted, sold at full or partial value, or put into a family corporation or trust with a different person named as manager.
A business plan and a transition plan can help your successfully transfer the business. If you are relying on a set income from the store, it is important to identify the role you will play in ensuring you receive it, and to have a contingency plan if it is not able to meet the goals.
Protecting the business against inter-family disputes should be discussed with a lawyer prior to transfer. Divorce, death, and changes in income can lead to problems between family members.
Ensure the person who is taking over the keys to the family store has the knowledge they need to operate it. If this person has not been active in all aspects of the business, they will require training. You will want to begin this process at least six months to a year prior to transferring the business.
Discuss with all family members what each person’s role, if any, will be in the business throughout the succession, and after, if you are keeping a portion of ownership.
Create a succession timeline and plan based on both of your needs. Some owners prefer a gradual turnover, while others do so all at once.
Accept that some things with the business will change. New products and technology are changing the way businesses operate and a fresh set of eyes may identify areas that are currently not performing as well as they should. Encourage your family to put their own personal stamp on the store.
We at the Chamber encourage all stores and family businesses to use our resources to increase their ability to be successful and continue to grow our community. Visit our Online Program On-Demand Library to discover educational tools to not only grow your business but also as a business owner.
Sally Dickinson Discusses Fitchburg’s Role in the
Career of Helicopter Inventor Igor Sikorsky
The Fitchburg Historical Society will host a talk on Wednesday, October 24 at 6 p.m. by Sally Dickinson, at the release party for her new paperback book The Missing Links to the Igor Sikorsky Story: His Struggle to Survive the Years between 1924 and 1929.
Dickinson discovered a large cache of historical documents about Sikorsky’s earliest years in America. She has written up the story in her new book, which she will be selling and signing at the Fitchburg Historical Society. The party will also feature a brief talk on some of the highlights of Dickinson’s research into the relationship between the aviation pioneer and his business partner Arnold Dickinson, a prominent business leader in Fitchburg.
Sikorsky emigrated to the US from Russia in 1919, escaping from the Soviet Revolution. The Wright Brothers flight had happened less than 20 years earlier, but Sikorsky imagined that large airplanes could move people, cargo and mail. After arriving in the states, he created businesses to design those modern airplanes, inventing some new forms of commercially successful planes. Ultimately, he invented amphibious airplanes and (most famously) invented the helicopter, a huge innovation in engineering and technology.
But how did a recent immigrant start and maintain a major manufacturing company in a brand new industry? Sikorsky needed to work with American businessmen to support him in his inventions and to create a successful company within short years of arriving in the US. As told in Dickinson’s new book, Sikorsky’s story includes great victories and terrible crashes. It also includes the race to fly from New York to Paris, and the daredevil age of pilots racing each other and risking death to fly nonstop between continents.
Sally Dickinson is from Leominster, went to Leominster High and Skidmore College. After raising a family and then working as a sales representative with Brown and Bigelow, a manufacturer of business promotional materials, she opened her own business, Portals Business Promotions, in the 1970’s, when independent women-owned businesses were still relatively rare.
As the President of the Board of Directors of the Fitchburg Historical Society, she headed up the Capital Campaign that allowed the Historical Society to purchase and renovate Phoenix Building on Main Street, a project that lasted over 5 years and raised more than 3 million dollars. She wrote a short booklet for the Historical Society: The Dickinson Family Story: From Handmade Boots to Amphibious Aircraft.
An “art tour” is a sort of voyage of discovery for art lovers. The idea is for patrons to be able to see what the arts have to offer in a particular city or region. Artists and art gallery owners come together for a day (or two) to show off the artwork being created in that area, sometimes to witness even the very act of creation itself. Such will be the exciting goings-on over the weekend of October 27 and 28 in Fitchburg, Mass., and vicinity.
“Fitchburg Open Studios” was organized by four stars of the Fitchburg art scene: gallery owner Tamar Russell Brown, pastel painter Lisa Regopoulos, and gallery owners Peter and Ann Capodagli. More than 20 artists responded to a call for artwork to be shown over the big weekend at many different sites, including the Fitchburg Art Museum and the various studios of participating artists. The 40,000 or so residents of the city of Fitchburg are about to find out just how much artistic talent the area has to offer.
Art lovers may need a full tank of gas or the equivalent energy on a bicycle for the entire weekend. The epicenter of the activities will be Fitchburg, of course, but the surrounding communities of Gardner, Leominster, Princeton and Townsend will be sites of studios where artists will be exhibiting.
“I had a dream to do this gallery,” says Tamar Russell Brown of Gallery Sitka at 454 Main Street in Fitchburg. The dream became a reality in May 2014 when Ms. Russell Brown started up a gallery at the Phoenix Park Mill in Shirley, and culminated with the grand opening of Gallery Sitka in downtown Fitchburg in July 2016. Some 40 area artists are represented by Sitka, and that gallery has an email list of over 100.
Art is a family affair for Tamar. “My father is an artist,” she reports, and her great aunt and great uncle were both painters. Though her father tried to warn her about the difficulty of making a living in the arts, she followed that dream anyway. The story goes all the way back to her teens, growing up in Tennessee. “I was collecting art at 15,” she recalls. Apparently she was destined for this calling in the art world from an early age.
Lisa Regopoulos paints pastels and considers herself an impressionistic artist. “I’m often trying to catch an image as if you had just caught a glimpse of it,” she says of her working methods. “You put more of yourself into the work,” she says, if you are working under that urgency of catching not just the visual fireworks of the images she paints en plein air (in the great outdoors) but also the mood, the feeling created while observing her subject matter. She’s out to capture, of course, an impression, and to communicate the excitement of a fleeting moment of beauty. The pastels are pigments held together by binders that allow tremendously vibrant colors to live on the paper surface, perhaps more strikingly than is possible with other materials.
Lisa will be opening her entire house to art lovers, hanging many recent paintings and working at the easel on a picture while her visitors look on. Some of the other artists who answered the call will be doing the same kind of demonstrations.
Ann and Peter Capodagli made their own dreams come true in 2008 when they opened the Boulder Art Gallery at 960 Main Street, in the shadow of the Rollstone Boulder, one of Fitchburg’s proudest landmarks and the inspiration for the name of the gallery. The lovely Upper Common area is the backdrop for the gallery, which also serves as Ann’s studio.
The Capodaglis were both teachers. Ann enjoyed 36 years as a Visual Arts instructor at Fitchburg High School, while Peter is a retired middle school science teacher who worked for 35 years in the Shirley school system. Ann is a watercolorist. Along with her watercolors, Ann will also be offering giclee prints and note cards at Boulder on both days of the art tour. Peter has been a collector of vintage art for many years. They are both dedicated to promoting and supporting local and regional artists.
Most of Boulder’s art is representational, Ms. Russell Brown says, with beautiful landscapes predominating. Sitka focuses more on abstract works that provide exciting interactions of pure color and texture.
Among the artists participating will be Doreen M. LaScola of Gardner, Ellen Schneeflock of Ashburnham, Pam Short of Lancaster, Linda Williams of Ashby, Leonard A. Haug of Princeton, Therese R. Blood of Westminster, as well as Brian G. Beaudoin, Randy LeSage, Christopher Di Nunzio, Kathryn Swantee, Iphigenia Burg, Jennifer Jones, Jen Hemenway, Gail Bloom, Sally Sargent, Kate Shaffer, Priscilla Mavrikis Walker, Keven McCarthy and Wil Darcangelo.
Ms. Russell Brown has created a special map to guide art lovers to all the participating studios and galleries. Go to fitchburgopenstudios.com for the map and more information about the big weekend.
When the workday ends and the lights go down, Custom Cleaning Service of Peabody, Inc. gets to work. “We operate as our clients’ silent partner after business hours,” says Adam Paicos, of Templeton, who now serves as Director of Operations and oversees the company’s expansion into North Central MA. “We are not often seen, but we ensure facilities are clean, secure, and ready for business each day while serving as the eyes and ears for our clients when they are not on site.”
Discover local business stories through our Inside North Central Massachusetts Podcast series. Listen as Chamber members share their journeys, insights, and contributions to our thriving regional business community.
Looking for your next opportunity? Explore current job openings from employers across North Central Massachusetts on our Jobs Board. Whether you’re starting a new career or making a change, you’ll find a variety of local positions available to help you take the next step.
CapEx Facility Services & Construction · Leominster, MA
TaraVista Behavioral Health Center · Harvard, MA
DRS Power Technology, Inc. · Fitchburg, MA
AIS · Leominster, MA